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A cell protection screen reveals potent inhibitors of multiple stages of the hepatitis C virus life cycle

The hepatitis C virus (HCV) life cycle involves multiple steps, but most current drug candidates target only viral replication. The inability to systematically discover inhibitors targeting multiple steps of the HCV life cycle has hampered antiviral development. We present a simple screen for HCV an...

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Hlavní autoři: Chockalingam, Karuppiah, Simeon, Rudo L., Rice, Charles M., Chen, Zhilei
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840489/
https://ncbi.nlm.nih.gov/pubmed/20142494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0915117107
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