Sequential rounds of RNA-dependent RNA transcription drive endogenous small-RNA biogenesis in the ERGO-1/Argonaute pathway

Argonaute (AGO) proteins interact with distinct classes of small RNAs to direct multiple regulatory outcomes. In many organisms, including plants, fungi, and nematodes, cellular RNA-dependent RNA polymerases (RdRPs) use AGO targets as templates for amplification of silencing signals. Here, we show t...

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Detalhes bibliográficos
Main Authors: Vasale, Jessica J., Gu, Weifeng, Thivierge, Caroline, Batista, Pedro J, Claycomb, Julie M., Youngman, Elaine M., Duchaine, Thomas F., Mello, Craig C., Conte, Darryl
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840456/
https://ncbi.nlm.nih.gov/pubmed/20133583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911908107
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