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Structure of Vibrio cholerae ToxT reveals a mechanism for fatty acid regulation of virulence genes

Cholera is an acute intestinal infection caused by the bacterium Vibrio cholerae. In order for V. cholerae to cause disease, it must produce two virulence factors, the toxin-coregulated pilus (TCP) and cholera toxin (CT), whose expression is controlled by a transcriptional cascade culminating with t...

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Bibliografiske detaljer
Main Authors: Lowden, Michael J., Skorupski, Karen, Pellegrini, Maria, Chiorazzo, Michael G., Taylor, Ronald K., Kull, F. Jon
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840316/
https://ncbi.nlm.nih.gov/pubmed/20133655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0915021107
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