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Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments
Cytokines are pleiotropic and readily diffusible messenger molecules, raising the question of how their action can be confined to specific target cells. The T cell cytokine interleukin-2 (IL-2) is essential for the homeostasis of regulatory T (Treg) cells that suppress (auto)immunity and stimulates...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840293/ https://ncbi.nlm.nih.gov/pubmed/20133667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812851107 |
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