Identification of an unconventional E3 binding surface on the UbcH5 ∼ Ub conjugate recognized by a pathogenic bacterial E3 ligase.

Gram-negative bacteria deliver a cadre of virulence factors directly into the cytoplasm of eukaryotic host cells to promote pathogenesis and/or commensalism. Recently, families of virulence proteins have been recognized that function as E3 Ubiquitin-ligases. How these bacterial ligases integrate int...

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Bibliografiska uppgifter
Huvudupphovsmän: Levin, Itay, Eakin, Catherine, Blanc, Marie-Pierre, Klevit, Rachel E., Miller, Samuel I., Brzovic, Peter S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2010
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840284/
https://ncbi.nlm.nih.gov/pubmed/20133640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914821107
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