Apurinic/apyrimidinic endonuclease APE1 is required for PACAP-induced neuroprotection against global cerebral ischemia

Inducible DNA repair via the base-excision repair pathway is an important prosurvival mechanism activated in response to oxidative DNA damage. Elevated levels of the essential base-excision repair enzyme apurinic/apyrimidinic endonuclease 1 (APE1)/redox effector factor-1 correlate closely with neuro...

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Autors principals: Stetler, R. Anne, Gao, Yanqin, Zukin, R. Suzanne, Vosler, Peter S., Zhang, Lili, Zhang, Feng, Cao, Guodong, Bennett, Michael V. L., Chen, Jun
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840276/
https://ncbi.nlm.nih.gov/pubmed/20133634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1000030107
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