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Involvement of Caspase Activation in Azaspiracid-Induced Neurotoxicity in Neocortical Neurons
Azaspiracids (AZAs) are a novel group of marine phycotoxins that have been associated with severe human intoxication. We found that AZA-1 exposure increased lactate dehydrogense (LDH) efflux in murine neocortical neurons. AZA-1 also produced nuclear condensation and stimulated caspase-3 activity wit...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840215/ https://ncbi.nlm.nih.gov/pubmed/20047973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp312 |
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