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Threshold size for optimal passive pulmonary targeting and retention of rigid microparticles in rats
The relationship between microparticle (MP) size and lung targeting efficiency, intra-lung distribution and retention time was systematically studied after intravenous administration of rigid fluorescent polystyrene MPs of various sizes (2, 3, 6 and 10μm) to Sprague-Dawley rats. Total fluorescence w...
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| Autors principals: | , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840186/ https://ncbi.nlm.nih.gov/pubmed/20043961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2009.12.019 |
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