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Targeted metabolic labeling of yeast N-glycans with unnatural sugars

Metabolic labeling of glycans with synthetic sugar analogs has emerged as an attractive means for introducing nonnatural chemical functionality into glycoproteins. However, the complexities of glycan biosynthesis prevent the installation of nonnatural moieties at defined, predictable locations withi...

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Bibliographic Details
Main Authors: Breidenbach, Mark A., Gallagher, Jennifer E. G., King, David S., Smart, Brian P., Wu, Peng, Bertozzi, Carolyn R.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840165/
https://ncbi.nlm.nih.gov/pubmed/20142501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911247107
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