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Targeted metabolic labeling of yeast N-glycans with unnatural sugars

Metabolic labeling of glycans with synthetic sugar analogs has emerged as an attractive means for introducing nonnatural chemical functionality into glycoproteins. However, the complexities of glycan biosynthesis prevent the installation of nonnatural moieties at defined, predictable locations withi...

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Main Authors: Breidenbach, Mark A., Gallagher, Jennifer E. G., King, David S., Smart, Brian P., Wu, Peng, Bertozzi, Carolyn R.
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840165/
https://ncbi.nlm.nih.gov/pubmed/20142501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911247107
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