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An atomic-level mechanism for activation of the kinesin molecular motors

Kinesin cytoskeletal motors convert the energy of ATP hydrolysis into stepping movement along microtubules. A partial model of this process has been derived from crystal structures, which show that movement of the motor domain relative to its major microtubule binding element, the switch II helix, i...

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Autori principali: Sindelar, Charles V., Downing, Kenneth H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840164/
https://ncbi.nlm.nih.gov/pubmed/20160108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0911208107
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