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Insight into the molecular mechanism of the multitasking kinesin-8 motor

Members of the kinesin-8 motor class have the remarkable ability to both walk towards microtubule plus-ends and depolymerise these ends on arrival, thereby regulating microtubule length. To analyse how kinesin-8 multitasks, we studied the structure and function of the kinesin-8 motor domain. We dete...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Peters, Carsten, Brejc, Katjuša, Belmont, Lisa, Bodey, Andrew J, Lee, Yan, Yu, Ming, Guo, Jun, Sakowicz, Roman, Hartman, James, Moores, Carolyn A
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964168/
https://ncbi.nlm.nih.gov/pubmed/20818331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.220
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