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Reactogenicity of live-attenuated Vibrio cholerae vaccines is dependent on flagellins
Cholera is a severe diarrheal disease caused by the motile Gram-negative rod Vibrio cholerae. Live-attenuated V. cholerae vaccines harboring deletions of the genes encoding cholera toxin have great promise for reducing the global burden of cholera. However, development of live vaccines has been hamp...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840140/ https://ncbi.nlm.nih.gov/pubmed/20160087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0915164107 |
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