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Back to the Future: Studying Cholera Pathogenesis Using Infant Rabbits

Cholera is a severe diarrheal disease, caused by Vibrio cholerae, for which there has been no reproducible, nonsurgical animal model. Here, we report that orogastric inoculation of V. cholerae into 3-day-old rabbits pretreated with cimetidine led to lethal, watery diarrhea in virtually all rabbits....

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Detalhes bibliográficos
Main Authors: Ritchie, Jennifer M., Rui, Haopeng, Bronson, Roderick T., Waldor, Matthew K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912669/
https://ncbi.nlm.nih.gov/pubmed/20689747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00047-10
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