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Membrane-anchored serine protease matriptase regulates epithelial barrier formation and permeability in the intestine
The intestinal epithelium serves as a major protective barrier between the mammalian host and the external environment. Here we show that the transmembrane serine protease matriptase plays a pivotol role in the formation and integrity of the intestinal epithelial barrier. St14 hypomorphic mice, whic...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840089/ https://ncbi.nlm.nih.gov/pubmed/20142489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903923107 |
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