Membrane-anchored serine protease matriptase regulates epithelial barrier formation and permeability in the intestine

The intestinal epithelium serves as a major protective barrier between the mammalian host and the external environment. Here we show that the transmembrane serine protease matriptase plays a pivotol role in the formation and integrity of the intestinal epithelial barrier. St14 hypomorphic mice, whic...

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Autors principals: Buzza, Marguerite S., Netzel-Arnett, Sarah, Shea-Donohue, Terez, Zhao, Aiping, Lin, Chen-Yong, List, Karin, Szabo, Roman, Fasano, Alessio, Bugge, Thomas H., Antalis, Toni M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2010
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840089/
https://ncbi.nlm.nih.gov/pubmed/20142489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903923107
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