Matriptase protects against experimental colitis and promotes intestinal barrier recovery

BACKGROUND & AIMS: Matriptase is a membrane-anchored serine protease encoded by Suppression of Tumorigenicity-14 (ST14) that is required for epithelial barrier homeostasis. However its functional role in inflammatory bowel disease (IBD) is unexplored. METHODS: Matriptase expression in control, C...

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Autori principali: Netzel-Arnett, Sarah, Buzza, Marguerite S., Shea-Donohue, Terez, Désilets, Antoine, Leduc, Richard, Fasano, Alessio, Bugge, Thomas H., Antalis, Toni M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288858/
https://ncbi.nlm.nih.gov/pubmed/22081509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21930
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