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Anti-SPARC oligopeptide inhibits laser-induced CNV in mice
It is known that SPARC gates VEGF-A signal transduction towards KDR, the primary angiogenic VEGF receptor. We sought to determine whether inhibition of SPARC activity using anti-SPARC peptide could inhibit laser-induced CNV by promoting binding of VEGF-A to FLT-1. We created anti-SPARC L-peptide and...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2840068/ https://ncbi.nlm.nih.gov/pubmed/20005890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.visres.2009.12.003 |
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