Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer

BACKGROUND: Aurora B kinase is an important mitotic kinase involved in chromosome segregation and cytokinesis. It is overexpressed in many cancers and thus may be an important molecular target for chemotherapy. AZD1152 is the prodrug for AZD1152-HQPA, which is a selective inhibitor of Aurora B kinas...

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Bibliografiset tiedot
Päätekijät: Gully, Christopher P, Zhang, Fanmao, Chen, Jian, Yeung, James A, Velazquez-Torres, Guermarie, Wang, Edward, Yeung, Sai-Ching Jim, Lee, Mong-Hong
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2010
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839967/
https://ncbi.nlm.nih.gov/pubmed/20175926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-42
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