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Antineoplastic effects of an Aurora B kinase inhibitor in breast cancer
BACKGROUND: Aurora B kinase is an important mitotic kinase involved in chromosome segregation and cytokinesis. It is overexpressed in many cancers and thus may be an important molecular target for chemotherapy. AZD1152 is the prodrug for AZD1152-HQPA, which is a selective inhibitor of Aurora B kinas...
Tallennettuna:
| Päätekijät: | , , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
BioMed Central
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2839967/ https://ncbi.nlm.nih.gov/pubmed/20175926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-42 |
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