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Screening small-molecule compound microarrays for protein ligands without fluorescence labeling with a high-throughput scanning microscope
We describe a high-throughput scanning optical microscope for detecting small-molecule compound microarrays on functionalized glass slides. It is based on measurements of oblique-incidence reflectivity difference and employs a combination of a y-scan galvometer mirror and an x-scan translation stage...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society of Photo-Optical Instrumentation Engineers
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2839802/ https://ncbi.nlm.nih.gov/pubmed/20210464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1117/1.3309743 |
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