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Desmin-regulated Lentiviral Vectors for Skeletal Muscle Gene Transfer

Lentiviral vectors (LVs) are highly attractive as a gene therapy agent as they are able to stably integrate their genomes in both dividing and nondividing cells and, in principle, provide long-term therapeutic benefit. However, their performance in skeletal muscle in adult animals has, to date, been...

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Detalhes bibliográficos
Main Authors: Talbot, Gillian E, Waddington, Simon N, Bales, Olivia, Tchen, Rose C, Antoniou, Michael N
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839432/
https://ncbi.nlm.nih.gov/pubmed/19935780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.267
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