Therapeutic and Tumor-specific Immunity Induced by Combination of Dendritic Cells and Oncolytic Adenovirus Expressing IL-12 and 4-1BBL

Recently, gene-based cytokine treatment has been actively pursued as a new promising approach in treating cancer. In an effort to augment the efficiency of antitumor effect by cytokine-mediated immunotherapy, we selected both interleukin (IL)-12 and 4-1BB ligand (4-1BBL) as suitable cytokines to ful...

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Detalhes bibliográficos
Main Authors: Huang, Jing-Hua, Zhang, Song-Nan, Choi, Kyung-Ju, Choi, Il-Kyu, Kim, Joo-Hang, Lee, Mingul, Kim, Hoguen, Yun, Chae-Ok
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839296/
https://ncbi.nlm.nih.gov/pubmed/19738604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.205
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