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Evidence for the Failure of Adeno-associated Virus Serotype 5 to Package a Viral Genome ≥8.2 kb
Limited packaging capacity hinders adeno-associated virus (AAV) gene therapy. A recent study seems to have provided a solution to this problem. Allocca et al. reported that AAV-5 could package an 8.9 kb vector genome. Here we tested whether this approach can be used to deliver a large genome for Duc...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2839223/ https://ncbi.nlm.nih.gov/pubmed/19904238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.256 |
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