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Segregation of type I collagen homo- and heterotrimers in fibrils
Normal type I collagen is a heterotrimer of two α1(I) and one α2(I) chains, but various genetic and environmental factors result in synthesis of homotrimers which consist of three α1(I) chains. The homotrimers completely replace the heterotrimers only in rare recessive disorders. In the general popu...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2839200/ https://ncbi.nlm.nih.gov/pubmed/18721810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.08.008 |
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