Myeloid DAP12-associating lectin (MDL)-1 regulates synovial inflammation and bone erosion associated with autoimmune arthritis

DNAX adaptor protein 12 (DAP12) is a trans-membrane adaptor molecule that transduces activating signals in NK and myeloid cells. Absence of functional Dap12 results in osteoclast defects and bone abnormalities. Because DAP12 has no extracelluar binding domains, it must pair with cell surface recepto...

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Detaylı Bibliyografya
Asıl Yazarlar: Joyce-Shaikh, Barbara, Bigler, Michael E., Chao, Cheng-Chi, Murphy, Erin E., Blumenschein, Wendy M., Adamopoulos, Iannis E., Heyworth, Paul G., Antonenko, Svetlana, Bowman, Edward P., McClanahan, Terrill K., Phillips, Joseph H., Cua, Daniel J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2010
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839155/
https://ncbi.nlm.nih.gov/pubmed/20212065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20090516
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