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Differential Regulation of the Dioxin-Induced Cyp1a1 and Cyp1b1 Genes in Mouse Hepatoma and Fibroblast cell lines

The xenobiotic metabolizing enzymes Cyp1a1 and Cyp1b1 can be induced by the environmental contaminant 2,3,7,8-tetrachlorodibenzo-ρ-dioxin (dioxin) via the Aryl Hydrocarbon Receptor (AhR). These genes are differentially induced by dioxin in different mouse cell lines. In the mouse hepatoma cell line...

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Autors principals: Beedanagari, Sudheer R., Taylor, Robert T., Hankinson, Oliver
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2839003/
https://ncbi.nlm.nih.gov/pubmed/20116417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2010.01.019
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