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Resveratrol Inhibits Dioxin-Induced Expression of Human CYP1A1 and CYP1B1 by Inhibiting Recruitment of the Aryl Hydrocarbon Receptor Complex and RNA Polymerase II to the Regulatory Regions of the Corresponding Genes

The CYP1A family of cytochrome P450s (CYPs), comprising CYP1A1, CYP1A2, and CYP1B1, plays a role in bioactivation of several procarcinogens to carcinogenic derivatives, and also in detoxification of several xenobiotic compounds. Resveratrol (3,4,5-trihydroxystelbine) is a naturally occurring compoun...

詳細記述

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書誌詳細
主要な著者: Beedanagari, Sudheer R., Bebenek, Ilona, Bui, Peter, Hankinson, Oliver
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696325/
https://ncbi.nlm.nih.gov/pubmed/19376845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfp079
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