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Factor VIIa interaction with endothelial cells and endothelial cell protein C receptor

Plasma coagulation factor VIIa (FVIIa) initiates the coagulation cascade by binding to its cofactor, tissue factor (TF) on cell surfaces, which eventually leads to fibrin deposition and platelet activation. Recent studies showed that FVIIa also binds to endothelial cell protein C receptor (EPCR), a...

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Detaylı Bibliyografya
Asıl Yazarlar: Pendurthi, Usha R, Rao, L. Vijaya Mohan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838982/
https://ncbi.nlm.nih.gov/pubmed/20156643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2010.01.026
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