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Factor VIIa interaction with endothelial cells and endothelial cell protein C receptor
Plasma coagulation factor VIIa (FVIIa) initiates the coagulation cascade by binding to its cofactor, tissue factor (TF) on cell surfaces, which eventually leads to fibrin deposition and platelet activation. Recent studies showed that FVIIa also binds to endothelial cell protein C receptor (EPCR), a...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2838982/ https://ncbi.nlm.nih.gov/pubmed/20156643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2010.01.026 |
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