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Mass Spectrometric Evidence for the Existence of Distinct Modifications of Different Proteins by 2(E), 4(E)-Decadienal

2(E), 4(E)-Decadienal (DDE), a lipid peroxidation product, was found to covalently modify Lys residues of different proteins by different reactions using mass spectrometry (MALDI-TOF-MS and LC-ESI-MS). DDE mainly formed Lys Schiff base adducts with cytochrome c and ribonuclease A at 10 min, but thes...

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Detalhes bibliográficos
Main Authors: Zhu, Xiaochun, Tang, Xiaoxia, Zhang, Jianye, Tochtrop, Gregory P., Anderson, Vernon E., Sayre, Lawrence M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838956/
https://ncbi.nlm.nih.gov/pubmed/20070074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx900379a
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