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Progressive histone alterations and proinflammatory gene activation: consequences of heme protein/iron-mediated proximal tubule injury

Rhabdomyolysis (Fe)-induced acute renal failure (ARF) causes renal inflammation, and, with repetitive insults, progressive renal failure can result. To gain insights into these phenomena, we assessed the impact of a single episode of glycerol-induced rhabdomyolysis on proinflammatory/profibrotic [TN...

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Detalhes bibliográficos
Main Authors: Zager, Richard A., Johnson, Ali C. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838607/
https://ncbi.nlm.nih.gov/pubmed/20032114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00683.2009
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