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High-pressure liquid chromatography analysis and single-dose disposition of tobramycin in human volunteers.
A sensitive and specific fluorometric high-pressure liquid chromatography technique was developed to measure both tobramycin and an internal standard (gentamicin C2). The assay utilizes direct extraction of the o-phthalaldehyde derivatives from serum and urine. Coefficients of variation were 7.9% (s...
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| Publicado no: | Antimicrob Agents Chemother |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1980
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283846/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7396455/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.17.4.649 |
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