Prostacyclin Inhibits Non-Small Cell Lung Cancer Growth by a Frizzled 9-Dependent Pathway That Is Blocked by Secreted Frizzled-Related Protein 1

The goal of this study was to assess the ability of iloprost, an orally active prostacyclin analog, to inhibit transformed growth of human non-small cell lung cancer (NSCLC) and to define the mechanism of iloprost's tumor suppressive effects. In a panel of NSCLC cell lines, the ability of ilopr...

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Main Authors: Tennis, Meredith A, Van Scoyk, Michelle, Heasley, Lynn E, Vandervest, Katherine, Weiser-Evans, Mary, Freeman, Scott, Keith, Robert L, Simpson, Pete, Nemenoff, Raphael A, Winn, Robert A
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838442/
https://ncbi.nlm.nih.gov/pubmed/20234818
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