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Sprouty-4 inhibits transformed cell growth, migration and invasion, and EMT and is regulated by Wnt7A through PPARγ in non-small cell lung cancer

Sprouty proteins are potent receptor tyrosine kinase inhibitors that antagonize growth factor signaling and are involved in lung development. However, little is known about the regulation or targets of Sprouty-4 (Spry4) in lung cancer. Our study aimed to determine the role of Spry4 in NSCLC. We foun...

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Main Authors: Tennis, MA, Van Scoyk, MM, Freeman, SV, Vandervest, KM, Nemenoff, RA, Winn, RA
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2888899/
https://ncbi.nlm.nih.gov/pubmed/20501643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-09-0400
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