Reactive Oxygen Species-Activated Akt/ASK1/p38 Signaling Pathway in Nickel Compound-Induced Apoptosis in BEAS 2B Cells

[Image: see text] Nickel compounds are carcinogenic to humans, possibly through induction of reactive oxygen species (ROS) that damage macromolecules including DNA and proteins. The aim of the present study is to elucidate the role of the ROS-mediated Akt/apoptosis-regulating signal kinase (ASK) 1/p...

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Detalhes bibliográficos
Main Authors: Pan, Jingju, Chang, Qingshan, Wang, Xin, Son, Youngok, Zhang, Zhuo, Chen, Gang, Luo, Jia, Bi, Yongyi, Chen, Fei, Shi, Xianglin
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2010
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838407/
https://ncbi.nlm.nih.gov/pubmed/20112989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx9003193
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