Reactive Oxygen Species-Activated Akt/ASK1/p38 Signaling Pathway in Nickel Compound-Induced Apoptosis in BEAS 2B Cells

[Image: see text] Nickel compounds are carcinogenic to humans, possibly through induction of reactive oxygen species (ROS) that damage macromolecules including DNA and proteins. The aim of the present study is to elucidate the role of the ROS-mediated Akt/apoptosis-regulating signal kinase (ASK) 1/p...

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Hauptverfasser: Pan, Jingju, Chang, Qingshan, Wang, Xin, Son, Youngok, Zhang, Zhuo, Chen, Gang, Luo, Jia, Bi, Yongyi, Chen, Fei, Shi, Xianglin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2010
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838407/
https://ncbi.nlm.nih.gov/pubmed/20112989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx9003193
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