MOBILIZATION STUDIES IN COMPLEMENT-DEFICIENT MICE REVEAL THAT OPTIMAL AMD3100 MOBILIZATION OF HEMATOPOIETIC STEM CELLS DEPENDS ON COMPLEMENT CASCADE ACTIVATION BY AMD3100-STIMULATED GRANULOCYTES

We reported that complement cascade (CC) becomes activated in bone marrow (BM) during mobilization of hematopoietic stem/progenitor cells (HSPCs) induced by granulocyte-colony stimulating factor (G-CSF) and C5 cleavage plays an important role in optimal egress of HSPCs. In the current work, we explo...

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Detalhes bibliográficos
Main Authors: Lee, HakMo, Wysoczynski, Marcin, Liu, Rui, Shin, Dong-Myung, Kucia, Magda, Botto, Marina, Ratajczak, Janina, Ratajczak, Mariusz Z.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838235/
https://ncbi.nlm.nih.gov/pubmed/20033053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2009.271
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