IMPAIRED MOBILIZATION OF HEMATOPOITEIC STEM/PROGENITOR CELLS IN C5-DEFCIENT MICE SUPPORTS THE PIVOTAL INVOLVEMENT OF INNATE IMMUNITY IN THIS PROCESS AND REVEALS NOVEL PROMOBILIZATION EFFECTS OF GRANULOCYTES

We reported that complement cascade (CC) becomes activated in bone marrow (BM) during granulocyte colony stimulating factor (G-CSF) mobilization of hematopoietic stem/progenitor cells (HSPCs) and demonstrated that while the third CC component (C3)-deficient mice are easy mobilizers, the fifth CC com...

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Autores principales: Lee, HakMo, Wan, Wu, Wysoczynski, Marcin, Liu, Rui, Zuba-Surma, Ewa K., Kucia, Magda, Ratajczak, Janina, Ratajczak, Mariusz Z.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777742/
https://ncbi.nlm.nih.gov/pubmed/19657368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2009.158
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