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In Silico-Accelerated Identification of Conserved and Immunogenic Variola/Vaccinia T-Cell Epitopes

Epitopes shared by the vaccinia and variola viruses underlie the protective effect of vaccinia immunization against variola infection. We set out to identify a subset of cross-reactive epitopes using bioinformatics and immunological methods. Putative T-cell epitopes were computationally predicted fr...

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Detalhes bibliográficos
Main Authors: Moise, Leonard, McMurry, Julie A., Buus, Soren, Frey, Sharon, Martin, William D., De Groot, Anne S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838212/
https://ncbi.nlm.nih.gov/pubmed/19559119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.06.018
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