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Identification of immunogenic HLA-B7 “Achilles' heel” epitopes within highly conserved regions of HIV

Genetic polymorphisms in class I human leukocyte antigen molecules (HLA) have been shown to determine susceptibility to HIV infection as well as the rate of progression to AIDS. In particular, the HLA-B7 supertype has been shown to be associated with high viral loads and rapid progression to disease...

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Autori principali: De Groot, Anne S., Rivera, Daniel S., McMurry, Julie A., Buus, Soren, Martin, William
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2553891/
https://ncbi.nlm.nih.gov/pubmed/18206276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.12.004
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