Dendritic Cells from HIV-1 Infected Individuals are Less Responsive to Toll-like Receptor (TLR) Ligands

We compared TLR responsiveness in PBMC from HIV-1-infected and uninfected individuals using the TLR agonists: TLR7 (3M-001), TLR8 (3M-002) and TLR7/8 (3M-011). Activation and maturation of plasmacytoid dendritic cells (pDC)were measured by evaluating CD86, CD40 and CD83 expression and myeloid dendri...

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Detalhes bibliográficos
Main Authors: Martinson, Jeffrey A., Roman-Gonzalez, Alejandro, Tenorio, Allan R., Montoya, Carlos J., Gichinga, Carolyne N., Rugeles, Maria T., Tomai, Mark, Krieg, Arthur M., Ghanekar, Smita, Baum, Linda L., Landay., Alan L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838175/
https://ncbi.nlm.nih.gov/pubmed/18334250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2008.01.007
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