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Influence of Disulfide-Stabilized Structure on the Specificity of Helper T-Cell and Antibody Responses to HIV Envelope Glycoprotein gp120

CD4(+) helper T cells specific for human immunodeficiency virus type 1 (HIV-1) are associated with control of viremia. Nevertheless, vaccines have had limited effectiveness thus far, in part because sequence variability and other structural features of the HIV envelope glycoprotein deflect the immun...

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Detalles Bibliográficos
Main Authors: Mirano-Bascos, Denise, Steede, N. Kalaya, Robinson, James E., Landry, Samuel J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838136/
https://ncbi.nlm.nih.gov/pubmed/20089653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02242-09
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