A V3 Loop-Dependent gp120 Element Disrupted by CD4 Binding Stabilizes the Human Immunodeficiency Virus Envelope Glycoprotein Trimer

Human immunodeficiency virus (HIV-1) entry into cells is mediated by a trimeric complex consisting of noncovalently associated gp120 (exterior) and gp41 (transmembrane) envelope glycoproteins. The binding of gp120 to receptors on the target cell alters the gp120-gp41 relationship and activates the m...

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Detaylı Bibliyografya
Asıl Yazarlar: Xiang, Shi-Hua, Finzi, Andrés, Pacheco, Beatriz, Alexander, Kevin, Yuan, Wen, Rizzuto, Carlo, Huang, Chih-Chin, Kwong, Peter D., Sodroski, Joseph
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2010
Konular:
Structure and Assembly
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838131/
https://ncbi.nlm.nih.gov/pubmed/20089638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02587-09
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