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The Polarity Protein Par1b/EMK/MARK2 Regulates T Cell Receptor-Induced MTOC Polarization

Engagement of a T cell to an antigen-presenting cell (APC) induces the formation of an immunological synapse as well as reorientation of the microtubule-organizing center (MTOC) toward the APC. How signals emanating from the T cell receptor (TCR) induce MTOC polarization is not known. One group of p...

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Detalhes bibliográficos
Main Authors: Lin, Joseph, Hou, Kirk K., Piwnica-Worms, Helen, Shaw, Andrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837933/
https://ncbi.nlm.nih.gov/pubmed/19553522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803887
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