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Identification and characterization of a novel variant of the human P2X(7) receptor resulting in gain of function
The P2X(7) receptor exhibits significant allelic polymorphism in humans, with both loss and gain of function variants potentially impacting on a variety of infectious and inflammatory disorders. At least five loss-of-function polymorphisms (G150R, R307Q, T357S, E496A, and I568N) and two gain-of-func...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2837825/ https://ncbi.nlm.nih.gov/pubmed/19838818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-009-9168-9 |
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