Identification and characterization of the novel reversible and selective cathepsin X inhibitors

Cathepsin X is a cysteine peptidase involved in the progression of cancer and neurodegenerative diseases. Targeting this enzyme with selective inhibitors opens a new possibility for intervention in several therapeutic areas. In this study triazole-based reversible and selective inhibitors of catheps...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Fonović, Urša Pečar, Mitrović, Ana, Knez, Damijan, Jakoš, Tanja, Pišlar, Anja, Brus, Boris, Doljak, Bojan, Stojan, Jure, Žakelj, Simon, Trontelj, Jurij, Gobec, Stanislav, Kos, Janko
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597618/
https://ncbi.nlm.nih.gov/pubmed/28904354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11935-1
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