Radiation-inducible Silencing of uPA and uPAR in vitro and in vivo in meningioma

Stereospecific radiation treatment offers a distinct opportunity for temporal and spatial regulation of gene expression at tumor sites by means of inducible promoters. To this end, a plasmid, pCArG-U2, was constructed by incorporating nine CArG elements (in tandem) of EGR1 gene upstream to uPA and u...

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Main Authors: Gogineni, Venkateswara Rao, Nalla, Arun Kumar, Gupta, Reshu, Gorantla, Bharathi, Gujrati, Meena, Dinh, Dzung H., Rao, Jasti S.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837517/
https://ncbi.nlm.nih.gov/pubmed/20198323
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