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Analysis of the Gastric H,K ATPase for Ion Pathways and Inhibitor Binding Sites

New models of the gastric H,K ATPase in the E(1)K and E(2)P states are presented as the first structures of a K(+) counter-transport P(2)-type ATPase exhibiting ion entry and exit paths. Homology modeling was first used to generate a starting conformation from the srCa ATPase E(2)P form (PDB code 1w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Munson, Keith, Law, Richard J., Sachs, George
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837483/
https://ncbi.nlm.nih.gov/pubmed/17425287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi062305h
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