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An Ion Gating Mechanism of Gastric H,K-ATPase Based on Molecular Dynamics Simulations
Gastric H,K-ATPase is an electroneutral transmembrane pump that moves protons from the cytoplasm of the parietal cell into the gastric lumen in exchange for potassium ions. The mechanism of transport against the established electrochemical gradients includes intermediate conformations in which the t...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2527272/ https://ncbi.nlm.nih.gov/pubmed/18567633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.128025 |
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