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Direct TLR2 Signaling Is Critical for NK Cell Activation and Function in Response to Vaccinia Viral Infection

Natural killer (NK) cells play an essential role in innate immune control of poxviral infections in vivo. However, the mechanism(s) underlying NK cell activation and function in response to poxviruses remains poorly understood. In a mouse model of infection with vaccinia virus (VV), the most studied...

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Detalhes bibliográficos
Main Authors: Martinez, Jennifer, Huang, Xiaopei, Yang, Yiping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837413/
https://ncbi.nlm.nih.gov/pubmed/20300608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000811
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