Dynamic Imaging of Experimental Leishmania donovani-Induced Hepatic Granulomas Detects Kupffer Cell-Restricted Antigen Presentation to Antigen-Specific CD8(+) T Cells

Kupffer cells (KCs) represent the major phagocytic population within the liver and provide an intracellular niche for the survival of a number of important human pathogens. Although KCs have been extensively studied in vitro, little is known of their in vivo response to infection and their capacity...

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Bibliographic Details
Main Authors: Beattie, Lynette, Peltan, Adam, Maroof, Asher, Kirby, Alun, Brown, Najmeeyah, Coles, Mark, Smith, Deborah F., Kaye, Paul M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837408/
https://ncbi.nlm.nih.gov/pubmed/20300603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000805
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